Cardiac Fibrosis: Definition, Clinical Significance, and Overview
Cardiac Fibrosis is the abnormal buildup of fibrous connective tissue within the heart, most often in the myocardium (heart muscle). In plain terms, it is “scarring” or “stiffening” of heart tissue that can disrupt pumping and electrical conduction. It is a pathologic process discussed across cardiology, heart failure medicine, electrophysiology, and cardiac imaging. It is commonly referenced when interpreting echocardiography and cardiac magnetic resonance (CMR) findings, and when assessing prognosis.