Structural Heart Disease: Definition, Clinical Significance, and Overview
Structural Heart Disease refers to abnormalities of the heart’s anatomy that affect how blood flows through the heart and great vessels. It is a clinical domain spanning diagnosis (imaging and hemodynamics) and treatment (medical therapy, catheter-based intervention, and surgery). The term is commonly used in cardiology, cardiothoracic surgery, echocardiography, and multidisciplinary “heart team” decision-making. It most often centers on cardiac valves, congenital defects, chambers, and adjacent structures such as the aorta.