Spontaneous Coronary Artery Dissection is a non-traumatic, non-iatrogenic tear or separation within a coronary artery wall. It is a cause of acute coronary syndrome (ACS) and myocardial infarction (MI) that is distinct from atherosclerotic plaque rupture. It belongs to cardiovascular pathology and coronary artery anatomy, and it is most often discussed in emergency and acute cardiology settings. It is commonly identified during evaluation for chest pain with electrocardiography (ECG), cardiac biomarkers (e.g., troponin), and coronary angiography.

Coronary Microvascular Dysfunction is abnormal function of the heart’s small coronary vessels that can limit blood flow to the myocardium. It is a cardiovascular pathophysiology concept most often discussed in patients with angina or ischemia despite non-obstructive epicardial coronary arteries. It sits at the intersection of coronary anatomy, endothelial biology, and ischemic heart disease evaluation. It is commonly used in chest pain assessment pathways, stress testing interpretation, and invasive coronary function testing.

Microvascular Angina is chest pain (angina) caused by dysfunction of the heart’s small coronary vessels rather than major coronary artery blockages. It is a clinical syndrome in cardiology that sits at the intersection of ischemic heart disease, coronary physiology, and symptom assessment. It is commonly discussed when patients have angina-like symptoms but non-obstructive coronary arteries on angiography or coronary CT angiography (CCTA). It is also used in the evaluation of ischemia with non-obstructive coronary arteries (INOCA) and related coronary microvascular dysfunction.

Cardiac Syndrome X is a clinical syndrome of angina-like chest pain with evidence of ischemia but without obstructive coronary artery disease on angiography. It belongs to the domain of cardiovascular pathophysiology and diagnostic cardiology. It is most commonly discussed when patients have persistent symptoms despite “normal” or non-obstructive epicardial coronary arteries. In modern practice, it overlaps with the concept of microvascular angina and ischemia with non-obstructive coronary arteries (INOCA).

Cardiac Metastasis means cancer spread to the heart or pericardium from a tumor that started elsewhere in the body. It is a pathology topic that intersects cardiology, oncology, imaging, and cardiothoracic surgery. It is most often discussed when a patient with known or suspected malignancy develops new cardiac symptoms or abnormal tests. It is commonly identified using echocardiography, cardiac magnetic resonance imaging (cardiac MRI), computed tomography (CT), or positron emission tomography (PET).

Atrial Myxoma is a primary (originating in the heart) benign tumor that most often arises in the atria. It is a cardiac pathology relevant to anatomy, hemodynamics, and embolic risk. It is commonly discussed in cardiology, emergency care, and cardiothoracic surgery because it can mimic more common diseases. It is most often identified on echocardiography and confirmed after surgical excision by pathology.

A Cardiac Tumor is an abnormal mass arising in or involving the heart. It is a topic in cardiovascular pathology and cardiac anatomy with major diagnostic and surgical relevance. Cardiac Tumor is commonly discussed when evaluating unexplained embolic events, murmurs, arrhythmia, or heart failure symptoms. It is most often identified using cardiac imaging such as echocardiography, cardiac magnetic resonance imaging (MRI), or cardiac computed tomography (CT).

Endomyocardial Biopsy is a procedure that removes tiny samples of heart muscle (myocardium) for microscopic analysis. It is a diagnostic test used in cardiology to identify specific causes of cardiomyopathy, myocarditis, and transplant rejection. It is most commonly performed via a catheter placed into the right side of the heart. It helps connect clinical findings to tissue-level pathology when noninvasive tests are inconclusive.

Cardiac Amyloidosis is a myocardial disease caused by abnormal protein deposits (amyloid) infiltrating the heart. It is a form of restrictive cardiomyopathy that can lead to heart failure, arrhythmias, and conduction disease. It is most often discussed in cardiology, internal medicine, hematology, and cardiac imaging. It is commonly evaluated with echocardiography, cardiac magnetic resonance (CMR), nuclear scintigraphy, and sometimes endomyocardial biopsy.

Cardiac Sarcoidosis is heart involvement by sarcoidosis, an inflammatory disease characterized by granulomas. It is a cardiac pathology that can affect the myocardium (heart muscle) and the cardiac conduction system. It is commonly discussed in cardiology, electrophysiology, and heart failure care because it can cause arrhythmias and cardiomyopathy. It is most often identified through clinical evaluation combined with cardiac imaging and rhythm assessment.