Coronary Microvascular Dysfunction: Definition, Clinical Significance, and Overview
Coronary Microvascular Dysfunction is abnormal function of the heart’s small coronary vessels that can limit blood flow to the myocardium. It is a cardiovascular pathophysiology concept most often discussed in patients with angina or ischemia despite non-obstructive epicardial coronary arteries. It sits at the intersection of coronary anatomy, endothelial biology, and ischemic heart disease evaluation. It is commonly used in chest pain assessment pathways, stress testing interpretation, and invasive coronary function testing.